MSCI 530 Quiz 4 Fatty Acid

MSCI 530 Quiz 4: Fatty Acid and Triglyceride Metabolism

1. In what part of the compartment of the cell does fatty acid synthesis take place?
2. Which of these hormones does not play a role in the mobilization of fatty acids from triacyglycerol stores in the fasted state?
3. The liver is the primary site of fatty acid synthesis and also stores large amounts of triacylglycerols.
4. Whereas normal cells derive most of the fatty acids they hey need for membrane phospholipid synthesis from extracellualr sources, cancer cells derive theirs from de nove fatty acid synthesis.
5. The first fatty acid produced in the de novo fatty acid synthesis pathway is;
6. Which of these is not a source of acetyl-CoA used for fatty acid synthesis?
7. The activity of acetyl-CoA carboxylase is promoted by these factors except;
8. The conversion of palmitic acid to palmitoleic acid is catalyzed by this enzyme;
9. A 2-month old baby who has been on a skimmed milk-based formula since birth because the mother was HIV positive, has recently developed scaly dermatitis, alopecia, easy bruising and is lagging in developmental milestones. The patient is diagnosed with Essential Fatty Acid deficiency – which of these fatty acids will have normal levels in this patient?
10. The most abundant polyunsaturated fatty acid in the human central nervous system is __________ and it is known to modulate phosphatidylserin ebiosynthesis and neural signaling.
11. The major site of tAG storage in humans is the;
12. Dietary TAG are transported by ____ in the blood stream;
13. In which of these tissues does the synthesis of TAG begin with a monoacylglycerol rather than glycerol 3-phosphate and fatty acyl- CoA?
14. This lipoprotein has the highest protein to lipid ratio(density) content relative to the others;
15. The plasma level of dietary triglycerides and cholesteryl esters will be significantly diminished if the synthesis of this lipoprotein is impaired?
16. Which of these is a component of a nascent chylomicron;
17. Which of these enzymes does not play a role in ethanol metabolism?
18. What is the fate of acetate generated from ethanol metabolism in hepatocytes when the ethanol is consumed without a carbohydrate meal?
19. Chronic ethanol consumption can impair Vitamin A metabolism by competitively inhibiting retinol dehydrogenase (the enzyme that converts retinol to all-trans retinal used in forming rhodopsin).
20. Ethanol can be used in the treatment methnaol and ethylene glycol poisonings by competitive inhibition of alcohol dehydrogenase. The danger of this treatment option is;