ETHC 210 Quiz Genetic Basis

ETHC 210 Quiz The Genetic Basis of Cancer

Covers the Learn material from Module 6: Week 6.

1. Skin damage and skin cancer is caused by ultraviolet light striking DNA and causing thymine dimers or even cutting the DNA. In most cases this causes death of the skin cell. But cancer is uncontrolled cell growth. How can exposure to light cause uncontrolled cell growth when it mostly kills cells? Chose an answer which best answers this question
2. The mutation which causes sickle cell disease can be classified as a point mutation and also a missense mutation.
3. Different genes have different spontaneous mutation rates.
4. Cancer is genetic because it is caused by changes in DNA but not usually inherited.
5. The two genetic diseases based on mutation of globin genes (globin proteins make up hemoglobin) are sickle cell disease and beta thalassemia.
6. The normal function of a tumor suppressor gene is to keep the cell cycle running at the appropriate rate for a particular cell type.
7. The genetic mutation which causes sickle cell disease is a change in one amino acid of hemoglobin and is based on one nucleotide mutational change (point mutation).
8. A tumor is cancerous or malignant if it infiltrates nearby tissue. This inltration and spreading is called metastasis.
9. Mutation can affect any part of the genome.
10. Which of the following is true about mutations?
11. DNA from cancer cells can;
12. Which of the following is true about the triplet code?
13. Translation is a process which;
14. Hela cells;
15. If a mutation occurs in the gametes before mitosis;
16. This beneficial mutation is found in about 1% of the general population and it tends to protect them from AIDs.
17. Which of the following are sources of potential mutation are found in our typical human environments?
18. A deletion mutation removes DNA. For example small deletion mutations in the “Y” chromosome causes male infertility.
19. Which of the following is true about osteogenesis imperfecta?
20. Cancer tumors grow and spread by inducing formation of blood vessels to nourish them. This is called;
21. A point mutation that changes a codon specifying an amino acid into a “stop” codon UAA, UAG or UGA is a nonsense mutation.
22. Splice site mutations can cause mutation by which of the following mechanisms?
23. The single amino acid change in hemoglobin which is the basis for sickle cell disease causes;
24. HER2 breast cancer affects hundreds of thousands of women each year. A drug called Herceptin has been an effective cure for this type of breast cancer. Herceptin is a;
25. A mutation is an altered DNA sequence in an organism.